IMAD: a driving force behind innovation

The Institute participates in and leads numerous projects and studies aimed at improving patient care through new innovations and advancing knowledge. Find out about the latest fundamental and translational research projects and clinical studies. 

Clinical studies :

Therapeutic areas: Gastroenterology, Endoscopy, Oncology, Hepatology, Chronic Inflammatory Bowel Disease (IBD), Digestive Surgery, Patient Cohorts, Biobanks, Health Data Collection, Endometriosis, etc.

Fondamental and Translational Research Projects :

Research areas: Gut-Brain Axis, Microbiota, Developmental Origin of Health and Diseases (DOHAD), First 1,000 Days, Nutrition, Chronic Inflammatory Bowel Diseases (IBD), Metabolism, Chronic Diseases, Neurodevelopment, Digestive Cancers, Spinal Cord Injury Pathologies, Infectious Diseases,

Clinical Studies & Projects

HEPATIMGO Network

The Western France Autoimmune Liver Disease Study and Research Network brings together all the hepatology and gastroenterology departments of university hospitals in western France to form a network for care, research, and teaching in the field of autoimmune liver diseases.

Study network led by Dr. Jérôme GOURNAY

Link

> CHU de Nantes, Hépatites, GIRCI, prévention, biocollection

TOGAS – TOwards GAstric Cancer Screening Implementation in the European Union

There is no effective screening method in Europe for the prevention of gastric cancer. The overall objective of TOGAS is therefore to provide the missing evidence that can be used to design, plan, and implement appropriate gastric cancer prevention in the EU.

European project led at the IMAD Institute by Prof. Tamara MATYSIAK BUDNIK

 

Link

> CHU de Nantes, gastric cancer, prevention

AIDA – an AI diagnostic assistant for detecting lesions before gastric cancer

The AIDA project aims to develop and validate a multidisciplinary AI-powered assistant that will help clinicians prevent gastric cancer by diagnosing precancerous gastric inflammation and suggesting personalized therapies and follow-up care.

European project led at IMAD by Prof. Tamara MATYSIAK BUDNIK

 

Link

> CHU de Nantes, gastric cancer , prevention, IA,

ENDOMIC

ENDOMIC – Impact of gut microbiota on digestive disorders
in women with endometriosis

In the context of endometriosis, the project aims to better characterize the digestive disorders suffered by these patients, analyze the composition of their gut microbiota, and study its impact on digestive functions. The objective is to identify new treatments and/or improve current care.

+ Support from SanteDige

Translational research project led by Dr. Claire Cardaillac

Lien/contact

> endometriosis,  TENS Lab, Microbiota, CHU de Nantes

CELESTE – Nantes Cohort for Chronic Inflammatory Bowel Diseases

Cohort of IBD patients backed by a biobank (blood, microbiota, tissues) to enable better characterization, at the molecular and cellular level, of the heterogeneity of pathological immune mechanisms observed in different patients.

+ Support from SanteDige

Cohort and biobank project by Dr. Catherine LE BERRE

Link/contact

> Chronic Inflammatory Bowel Diseases, TENS and PhAN laboratories, Microbiota, Nantes University Hospital, Jules Verne Clinic (Nantes) and Confluent Clinic (Nantes), IBD-Next cluster, CIC-Imad

NEO-TOCC pilote

Pilot study of the value of personalized colonic tumoroids in predicting response to chemotherapy in patients with locally advanced non-metastatic colorectal cancer.

Led by Prof. Emilie Duchalais

+ Support from SanteDige

Translational research project led by Prof. Emilie DUCHALAIS

Link/contact

> Digestive cancers, TENS laboratory, Organoids, Nantes University Hospital, CIC-Imad